A study published in The Journal of Nutrition has concluded that the natural dietary supplement conjugated linoleic acid (CLA) reduces body fat in people who are overweight or obese. The study is the largest published scientific evidence to date showing that the natural supplement reduces the weight of fatty tissue in humans. The double-blind, randomised, placebo-controlled study confirms a series of previous animal and human studies, which concluded that CLA improves body composition by reducing fat and preserving muscle tissue.