Interstate Bakeries Corporation (NYSE: IBC), the nation's largest baker and distributor of fresh branded bread and cake, yesterday reported lower operating income and earnings per share for its 12-week second quarter ended November 18, 2000. The Company's operating income was $32,676,000 compared to the previous year's $50,143,000, while earnings per share on a diluted basis were $0.22, compared to the prior year's $0.40.