Snow Brand Milk Products Co. has closed down the plant at the centre of last year's food-poisoning outbreak. The site in Osaka manufactured low-fat milk and yoghurt. The closure of the plant in Osaka's Miyakojima Ward after 45 years of operation was marked without ceremony. Since 1956, the plant had been one of the company's major factories, supplying dairy products mostly to the Kansai region in western Japan.