Scientists from Purdue University are using breakthrough molecular research and other new technologies to slash the diagnosis time of Johne's disease (paratuberculosis), the little known, usually fatal infection that causes US$1bn in US cattle industry losses annually. Johne's disease is characterised by weight loss without loss of appetite, diarrhea, and finally wasting and death. The disease can attack all ruminants and scientists say it is closely related to the human Crohn's disease.